一名住院患者在中午 12 点服用了一颗含有 50 单位抗生素的药丸。到下午 1 点,患者体内的抗生素单位数减少了 12%。到下午 2 点,下午 1 点时血液中残留的抗生素又流失了 12%。已知抗生素含量的减少速率为每小时降低 12%,求下午 6 点时血液中残留的抗生素量。 一位医生考虑制定一个疗程,让患者在很长一段时间内每 6 小时服用一次药丸。已知 xn+1=50+(0.88)6 xn ,x_{n+1}=50+(0.88)^6\,x_n\,, 其中 xnx_n 表示服用第 nn 颗药丸后体内的抗生素单位数。 当 n→∞n\to\infty 时,xn→Lx_n\to L。确定 LL 的值。 证明:当 xn<Lx_n<L 时,xn+1>xnx_{n+1}>x_n; 当 xn>L 时,xn+1<xn .\text{当 } x_n>L \text{ 时,} x_{n+1}<x_n\,.

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完整解法

5((i))

1. Determine the time elapsed and the constant decay multiplier.

The number of hours from 12pm to 6pm is 66.
Since the antibiotic decreases by 12%12\% every hour, the multiplier is 1−0.12=0.881 - 0.12 = 0.88.

2. Calculate the amount of antibiotic remaining after 6 hours.

Amount remaining =50×(0.88)6= 50 \times (0.88)^6
=23.220…= 23.220\dots
≈23.2 units\approx 23.2 \text{ units} (to 3 s.f.)

答案

23.223.2 units

5((ii))((a))

1. Apply the limit to the recurrence relation by setting $x_{n+1}$ and $x_n$ to $L$.

As n→∞n \to \infty, xn→Lx_n \to L. Since xn+1x_{n+1} also approaches the same limit as nn grows indefinitely, we substitute LL into the given recurrence relation:
L=50+(0.88)6LL = 50 + (0.88)^6 L

2. Solve the linear equation for $L$.

L−(0.88)6L=50L - (0.88)^6 L = 50
L(1−0.886)=50L(1 - 0.88^6) = 50
L=501−0.886L = \frac{50}{1 - 0.88^6}
L≈93.354L \approx 93.354
L=93.4 (to 3 s.f.)L = 93.4 \text{ (to 3 s.f.)}

答案

93.493.4 (to 3 s.f.)

5((ii))((b))

1. Express the difference $x_{n+1} - x_n$ in terms of $L$ and $x_n$.

Consider the difference between consecutive terms:
xn+1−xn=50+(0.88)6xn−xnx_{n+1} - x_n = 50 + (0.88)^6 x_n - x_n
xn+1−xn=50−(1−0.886)xnx_{n+1} - x_n = 50 - (1 - 0.88^6)x_n
From part (ii)(a), the steady-state limit LL satisfies L=50+(0.88)6LL = 50 + (0.88)^6 L, which means 50=L(1−0.886)50 = L(1 - 0.88^6). Substituting this into the equation gives:
xn+1−xn=L(1−0.886)−xn(1−0.886)x_{n+1} - x_n = L(1 - 0.88^6) - x_n(1 - 0.88^6)
xn+1−xn=(1−0.886)(L−xn)x_{n+1} - x_n = (1 - 0.88^6)(L - x_n)

2. Deduce the first inequality when $x_n < L$.

Since 0.88<10.88 < 1, the constant term (1−0.886)>0(1 - 0.88^6) > 0.
If xn<Lx_n < L, then (L−xn)>0(L - x_n) > 0.
Therefore, the product is positive:
(1−0.886)(L−xn)>0(1 - 0.88^6)(L - x_n) > 0
xn+1−xn>0x_{n+1} - x_n > 0
xn+1>xn (Shown)x_{n+1} > x_n \text{ (Shown)}

3. Deduce the second inequality when $x_n > L$.

Similarly, if xn>Lx_n > L, then (L−xn)<0(L - x_n) < 0.
Therefore, the product is negative:
(1−0.886)(L−xn)<0(1 - 0.88^6)(L - x_n) < 0
xn+1−xn<0x_{n+1} - x_n < 0
xn+1<xn (Shown)x_{n+1} < x_n \text{ (Shown)}

答案

As shown in the working.

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